Summary
Genetic polymorphism of the glucose dehydrogenase in white cells extracts from random adult Japanese was investigated using polyacrylamide gel isoelectric focusing or agarose gel isoelectric focusing, followed by a specific zymogram technique. Three common phenotypes, which might correspond to GDH 1, GDH 2 and GDH 2-1 reported by King and Cook (1981), were observed at the pIs between pH 6.56–6.76 on the gel. No phenotypes with GDH 3 component were detected so far. The allele frequency ofGDH 3 may be very low among Japanese. The results of family study suggest that these phenotypes are inherited in the autosomal codominant trait. The allele frequencies wereGDH 1=0.522 andGDH 2=0.478.
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Kera, Y., Yamasawa, K. & Komura, S. Genetic polymorphism of white blood cell glucose dehydrogenase in Japanese. Jap J Human Genet 28, 29–34 (1983). https://doi.org/10.1007/BF01897045
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DOI: https://doi.org/10.1007/BF01897045