Summary
One hundred and nine pairs of twin with anencephaly were ascertained during the period from 1969 to 1976 in Japan. The rate of concordance in anencephalic twins was 8.3% and seems to be higher than those of previous reports.
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Alter, M. 1962. Anencephalus, hydrocephalus and spina bifida.Arch. Neurol. 7:411–422.
Böök, J.A. and Rayner, S. 1950. A clinical and genetic study of anencephaly.Am. J. Hum. Genet. 2:61–84
Butler, N.R. and Alberman, E.D. (eds.) 1969. Perinatal Problems: The Second Report of the 1958 British Perinatal Mortality Survey. Livingstone, Edinburgh and London.
Carter, C.O. 1974. Clues to the aetiology of neural tube malformations.Dev. Med. Child Neurol. 16 (Suppl. 32):3–15
Carter, C.O., David, P.A., and Laurence, K.M. 1968. A family study of major central nervous system malformations in South Wales.J. Med. Genet. 5:81–106.
Carter, C.O. and Evans, K. 1973. Spina bifida and anencephalus in Greater London.J. Med. Genet. 10:209–234
Coffey, V.P. and Jessop, W.J.E. 1957. A study of 137 cases of anencephaly.Br. J. Prev. Soc. Med. 11:174–180.
Czeizel, A. and Révész, C. 1970. Major malformations of the central nervous system in Hungary.Br. J. Prev. Soc. Med. 24:205–222.
deSa', D.J., Strong, S.J., and Corney, G. 1964. Anencephaly in one of monozygous twins.Biol. Neonate. 7:328–334.
DeHaan, Q.C. 1966. Monozygotic anencephalic twins.Obstet. Gynecol. 28:559–560
Dumoulin, J.G. and Gordon, M.E. 1959. Anencephaly in twins.J. Obstet. Gynaecol. Br. Emp. 66:964–968.
Elwood, J.H. and Nevin, N.C. 1973. Factors associated with anencephalus and spina bifida in Belfast.Br. J. Prev. Soc. Med. 27:73–83.
Frézal, J., Kelly, J., Guillemot, M.L., and Lamy, M. 1964. Anencephaly in France.Am. J. Hum. Genet. 16:336–350.
Gittelsohn, A.M. and Milham, S., Jr. 1965. Vital record incidence of congenital malformations in New York State. In:Genetics and the Epidemiology of Chronic Diseases,Neel, J.V., Shaw, M.W., and Schull, W.J., eds. (Public Health Service Publication No. 1163).U.S. Department of Health, Education, and Welfare, Washington, D.C., pp. 305–319.
Hay, S. and Wehrung, D.A. 1970. Congenital malformations in twins.Am. J. Hum. Genet. 22: 662–678.
Horowitz, I. and McDonald, A.D. 1969. Anencephaly and spina bifida in the Province of Quebec.Can. Med. Assoc. J. 100:748–755.
Imaizumi, Y. 1974. Statistical analysis on anencephaly, spina bifida and congenital hydrocephaly in Japan.Jap. J. Human Genet. 9:115–135.
James, W.H. 1976. Twinning and anencephaly.Ann.Hum. Biol. 3:401–409.
Janerich, D.T. and Piper, J. 1978. Shifting genetic patterns in anencephaly and spina bifida.J. Med. Genet. 15:101–105.
Lemire, R.J., Beckwith, J.B., and Warkany, J. 1977. Anencephaly. Raven Press, New York.
Lewis, L. 1960. A case of twin anencephalic pregnancy.Br. Med. J. 19:1500–1501.
Masterson, J.G. 1962. Empiric risk, genetic counseling and preventive measures in anencephaly.Acta Genet. (Basel) 12:219–229.
Ministry of Health and Welfare of Japan. 1977. Survey on Socio-economic Aspects of Vital Events-Plural Births, 1975. Health and Welfare Statistics Division, Minister's Secretariat. Tokyo.
Neel, J.V. 1958. A study of major congenital defects in Japanese infants.Am. J. Hum. Genet. 10: 398–445.
Overbeke, J. 1971. Anencephalie in Nederland 1951–1968. Cited from James (1976).
Record, R.G. and McKeown, T. 1951. Congenital malformations of the central nervous system: Data on 69 pairs of twins.Ann. Eugen. 15:285–292.
Rogers, S.C. 1976. Anencephalus, spina bifida, twins, and teratoma.Br. J. Prev. Soc. Med. 30: 26–28.
Rogers, S.C. and Weatherall, J.A.C. 1976. Anencephalus, spina bifida and congenital hydrocephalus. England and Wales 1964–1972. HMSO, London.
Stevenson, A.C., Johnston, H.A., Stewart, M.I.P., and Golding, D.R. eds. 1966. Malformations of structures developed from the neural tube (B1–B7). Chapter 4 in Congenital Malformations,Bull. World Health Org. 34, Suppl.: pp. 25–34.
Symonds, E.M. 1965. Anencephaly and hydrocephaly in a twin pregnancy: Report of case.Obstet. Gynecol. 26:414–416.
Towell, M.E. 1961. Dizygotic anencephalic twins (microcephaly craniorhachischisis): Case report.J. Obstet. Gynaecol. Br. Commonw. 68:303–306.
Williamson, E.M. 1965. Incidence and family aggregation of major congenital malformations of central nervous system.J. Med. Genet. 2:161–172.
Wilson, J.K. 1955. Mono-amniotic multiple pregnancy.J. Obstet. Gynaecol. Br. Emp. 62:605–609.
Yen, S. and MacMahon, B. 1968. Genetics of anencephaly and spina bifida.Lancet 2:623–626.
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Imaizumi, Y. Concordance and discordance of anencephaly in 109 twin pairs in Japan. Jap J Human Genet 23, 389–393 (1978). https://doi.org/10.1007/BF01908194
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DOI: https://doi.org/10.1007/BF01908194