Abstract
In vitro antimicrobial activity of telavancin, a rapidly bactericidal lipoglycopeptide, was evaluated against 1500 strains of MRSA recently isolated in Japan. Telavancin had potent activity, with MIC values that ranged from 0.12 μg/ml to 0.5 μg/ml and a MIC90 value of 0.5 μg/ml. The MIC90s of vancomycin and linezolid were 1.0μg/ml and 2 μg/ml, respectively. No vancomycin intermediate resistant or vancomycin-resistant MRSAs were detected in this surveillance study.
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Hatano, K., Matsuzaki, K., Sato, Y. et al. In Vitro Antimicrobial Activity of Telavancin against Methicillin-resistant Staphylococcus aureus Clinical Isolates from Japan (2006). J Antibiot 60, 709–712 (2007). https://doi.org/10.1038/ja.2007.91
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DOI: https://doi.org/10.1038/ja.2007.91