Abstract
A part of the new biosynthetic gene cluster for 2-deoxystreptamine-containing antibiotics was identified from Streptoalloteichus hindustanus. The alloH gene in the gene cluster was deduced to encode 2-deoxy-scyllo-inosose synthase and the expressed protein AlloH was confirmed to have this enzyme activity. Furthermore, biochemical properties of AlloH were studied.
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Hirayama, T., Tamegai, H., Kudo, F. et al. Biosynthesis of 2-Deoxystreptamine-containing Antibiotics in Streptoalloteichus hindustanus JCM 3268: Characterization of 2-Deoxy-scyllo-inosose Synthase. J Antibiot 59, 358–361 (2006). https://doi.org/10.1038/ja.2006.51
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DOI: https://doi.org/10.1038/ja.2006.51
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