Abstract
An antifungal pentaene macrolide TPU-0043 was isolated from Streptomyces sp. TP-A0625. The absolute configuration of TPU-0043 was determined to be 2R-(n-butyl)-16-methyl-3S,5S,7S,9R,11R,13R,15S,26S,27R-nonahydroxyoctacosa-16,18,20,22,24-pentaenoic acid, 27-lactone, by X-ray crystallography of its 13-p-bromobenzenesulfonyl derivative.
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Igarashi, Y., In, Y., Ishida, T. et al. Absolute Configuration of TPU-0043, a Pentaene Macrolide from Streptomyces sp.. J Antibiot 58, 523–525 (2005). https://doi.org/10.1038/ja.2005.71
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DOI: https://doi.org/10.1038/ja.2005.71