Abstract
Four new antibiotics, sesquicillins B to E were isolated from the culture broth of Albophoma sp. FKI-1778 together with known sesquicillin (sesquicillin A in this paper). The structures of sesquicillins were elucidated by spectroscopic studies including various NMR experiments. All sesquicillins have a common pyrano-diterpene skeleton. Sesquicillins showed moderate inhibitory activity against the growth of Artemia salina (brine shrimps) and Jurkat cells.
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Uchida, R., Imasato, R., Yamaguchi, Y. et al. New Sesquicillins, Insecticidal Antibiotics Produced by Albophoma sp. FKI-1778. J Antibiot 58, 397–404 (2005). https://doi.org/10.1038/ja.2005.50
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DOI: https://doi.org/10.1038/ja.2005.50
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