Abstract
Purpose To determine whether prilocaine is a more comfortable local infiltration anaesthetic agent than the more widely used lignocaine for minor eyelid procedures.
Methods A prospective randomised study was undertaken to compare the discomfort between local infiltration of plain 2% prilocaine versus its equivalent, plain 2% lignocaine. One hundred and twenty-five patients were recruited. Pain was assessed subjectively using a visual analogue pain score, graded from 0 to 10.
Results The mean pain score for the prilocaine group was 1.82 compared with 3.19 for the lignocaine group. Using the Mann-Whitney U-test for significance, U = 1236.5; p < 0.001.
Conclusion Prilocaine is a more comfortable local infiltration anaesthetic agent than lignocaine when used for minor eyelid procedures.
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Burton, A., Backhouse, O. & Metcalfe, T. Prilocaine versus lignocaine for minor lid procedures. Eye 14, 594–596 (2000). https://doi.org/10.1038/eye.2000.149
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DOI: https://doi.org/10.1038/eye.2000.149