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Greater severity of clinical features in older patients with Duane's retraction syndrome

Abstract

Duane's retraction syndrome (DRS) is a well-described entity. However, the possibility of this condition having progressive features has not been previously documented. We studied 21 consecutive patients with this disorder and found that the incidence of severe retraction on adduction, the occurrence of enophthalmos in the primary position and the presence of upshoots and downshoots were significantly higher in adults with type I DRS than in children. Awareness that the clinical features may increase in severity is important as parental counselling, coupled with effective communication to general practitioners, can prompt re-referral should such problems arise. Surgical intervention as a consequence, becomes an available option to correct disease progression.

References

  1. Duane A . Congenital deficiency of abduction associated with impairment of adduction, retraction movements, contraction of palpebral fissure and oblique movements of the eye. Arch Ophthalmol 1905;34:133–59.

    Google Scholar 

  2. Miller NR, Kiel SM, Green WR, Clark AW . Unilateral Duane's retraction syndrome (type I). Arch Ophthalmol 1982;100:1468–72.

    CAS  Article  Google Scholar 

  3. Hotchkiss MG, Miller NR, Clarke AW, Green WR . Bilateral Duane's retraction syndrome. Arch Ophthalmol 1980;98:870–4.

    CAS  Article  Google Scholar 

  4. Metz HS, Scott AB, Scott WE . Horizontal saccadic velocities in Duane's syndrome. Am J Ophthalmol 1975;80:901–6.

    CAS  Article  Google Scholar 

  5. Scott AB, Wong GY . Duane's syndrome: an electro-myographic study. Arch Ophthalmol 1972;87:140–7.

    CAS  Article  Google Scholar 

  6. Huber A . Electrophysiology of the retraction syndromes. Br J Ophthalmol 1974;58:293–300.

    CAS  Article  Google Scholar 

  7. Jampolsky A . Surgical leashes and reverse leashes in strabismus surgical management. In: Symposium on strabismus. Transactions of the New Orleans Academy of Ophthalmology. St Louis: CV Mosby, 1978:244–53.

  8. Kraft SP . A surgical approach for Duane syndrome. J Pediatr Ophthalmol Strabismus 1988;25:119–30.

    CAS  Google Scholar 

  9. Rogers GL, Bremer DL . Surgical treatment of upshoots and downshoots in Duane's retraction syndrome. Ophthalmology 1984;91:1380–3.

    CAS  Article  Google Scholar 

  10. Von-Noorden GK, Murray E . Upshoots and downshoots in Duane's retraction syndrome. J Pediatr Ophthalmol Strabismus 1986;23:212–5.

    CAS  Google Scholar 

  11. Von-Noorden GK . Recession of both horizontal recti in Duane's retraction syndrome with elevation and depression of the adducted eye. Am J Ophthalmol 1992;114:311–3.

    CAS  Article  Google Scholar 

  12. Scott AB, Wong G, Jampolsky A . Pathogenesis in Duane's syndrome [abstract]. Invest Ophthalmol Vis Sci 1970;9:983.

    Google Scholar 

  13. Lee JP . Congenital extraocular muscle defects. Eye 1992;6:181–3.

    Article  Google Scholar 

  14. Bloom JN, Graviss ER, Mardelli PG . A magnetic resonance imaging study of upshoot-downshoot phenomenon of Duane's retraction syndrome. Am J Ophthalmol 1991;111:548–54.

    CAS  Article  Google Scholar 

  15. O'Malley ER, Helveston EM, Elis FD . Duane's retraction syndrome - plus. J Pediatr Ophthalmol Strabismus 1982;19:161–5.

    CAS  Google Scholar 

  16. Raab EL . Clinical features of Duane's syndrome. J Pediatr Ophthalmol Strabismus 1986;23:64–8.

    CAS  Google Scholar 

  17. Isenberg S, Urist MJ . Clinical observations in 101 consecutive patients with Duane's retraction syndrome. Am J Ophthalmol 1977;84:419–25.

    CAS  Article  Google Scholar 

Download references

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Noonan, C., O'Connor, M. Greater severity of clinical features in older patients with Duane's retraction syndrome. Eye 9, 472–475 (1995). https://doi.org/10.1038/eye.1995.109

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  • DOI: https://doi.org/10.1038/eye.1995.109

Keywords

  • Downshoots
  • Duane's retraction syndrome
  • Enophthalmos
  • Upshoots

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