Abstract
Understanding the management of non-insulin-dependent (type 2) diabetes (NIDDM) requires the grasp of three concepts. Firstly, the condition is steadily progressive and demands appropriate changes of therapy over time. Secondly, therapeutic aims must be set for three parameters: plasma lipids, plasma glucose and blood pressure. Thirdly, the condition is dangerous and regular screening for early complications is mandatory. In this brief review the nature of NIDDM is discussed and an approach to clinical management outlined.
Similar content being viewed by others
Article PDF
References
Hadden DR, Blair ALT, Wilson EA, et al. Natural history of diabetes presenting age 40–69 years: a prospective study of the influence of intensive dietary therapy. Q J Med 1986;230:579–98.
Rudenski AS, Hadden DR, Atkinson AB, Kennedy L, Matthew DR, Merrett JD, Pockaj B, Turner RC . Natural history of pancreatic islet B-cell function in type 2 diabetes mellitus studied over six years by homeostasis model assessment. Diabetic Med 1988;5:36–41.
Taylor R . Resistance to injection. Diabetic Med 1992;9:104–8.
Alberti KGMM, Gries FA . Management of non-insulin dependent diabetes mellitus in Europe: a consensus view. Diabetic Med 1988;5:275–81.
Pirart J . Diabete et complications degeneratives: presentation d'une etude prospective portant sur 4400 cas observes entre 1949-1973. Diabete Metab 1977;3:97–107.
Hanefield M, Schmechel H, Julius U, Fischer S, Schulze J, Schwanebeck U, et al. Five-year incidence of coronary heart disease related to major risk factors and metabolic control in newly diagnosed non-insulin dependent diabetes. Nutr Metab Cardiovasc Dis 1991;1:135–40.
UK Prospective Diabetes Study II. Reduction in HbA1c with basal insulin supplement, sulphonylurea or biguanide therapy in maturity onset diabetes. Diabetes 1985;61:32–6.
Klein R, Klein BEK, Moss SE, Davies MD, DeMets DL . The Wisconsin epidemiology study. III. Prevalence of risk of diabetic retinopathy when age at diagnosis is 30 or more years. Arch Ophthalmol 1984;102:527–32.
Teuscher A, Schnell H, Wilson PWF . Predisposition to hypertension and susceptibility to renal disease in insulin dependent diabetes mellitus. N Engl J Med 1988;318:140–5.
Mogensen CE . Longterm antihypertensive treatment inhibits progression of diabetic retinopathy. BMJ 1982;285:685–8.
Drury PL, Tarn A . Are the WHO criteria for hypertension appropriate in young insulin dependent diabetics? Diabetic Med 1985;2:79–82.
Day J . Management of non-insulin dependent diabetes. 1989.
Elgrably F, Costagliola D, Chwalow AJ, Varenne P, Slama G, Tchobroutsky G . Initiation of insulin treatment after 70 years of age: patient status 2 years later. Diabetic Med 1991;8:773–7.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Taylor, R. Management of non-insulin-dependent diabetes. Eye 7, 298–301 (1993). https://doi.org/10.1038/eye.1993.64
Issue Date:
DOI: https://doi.org/10.1038/eye.1993.64