Abstract
Autonomie innervation to the eye and ocular adnexae was assessed in seven patients with Lambert-Eaton Myasthenic Syndrome and 50 age-matched control subjects. Pupil responses to light were abnormal in 69% of LEMS patients, compared with 18% of the control group. Reflex tear production—a screening test for parasym-pathetic innervation to the lacrimal gland—was below the accepted normal limit in 69% of LEMS patients. Parasympathetic and sympathetic denervation hypersensitivity of the iris musculature were individually present in 57% of LEMS patients, compared with 6% of control subjects. The association between autonomie dysfunction and Lambert-Eaton Myasthenic Syndrome is discussed.
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Clark, C., Newsom-Davis, J. & Sanders, M. Ocular autonomic nerve function in Lambert-Eaton myasthenic syndrome. Eye 4, 473–481 (1990). https://doi.org/10.1038/eye.1990.61
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DOI: https://doi.org/10.1038/eye.1990.61
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