Abstract
Patients receiving antimalarial therapy, specifically hydroxychloroquine, for different periods were evaluated using contrast sensitivity test (CST) and results were compared with those of electro-retinography (EOG), and pattern visual evoked potential (PVEP), and a matching age control group. The results indicated CST to be most sensitive of the evaluated techniques particularly in patients under 40 years old. In 44.4% of the cases CST revealed macular dysfunction of which the other two methods of examination were not capable. Our findings suggest the CST is a reliable and practical method which could be used as an additional screening test for chloroquine maculopathy.
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Bishara, S., Matamoros, N. Evaluation of several tests in screening for chloroquine maculopathy. Eye 3, 777–782 (1989). https://doi.org/10.1038/eye.1989.121
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DOI: https://doi.org/10.1038/eye.1989.121
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