Abstract
The expression of dystrophin gene has been found to be regulated through different promoters in different tissues. To understand the mechanism of tissue specific selection of promoter DNA-protein interaction studies were carried out using tissue specific nuclear extracts. Several tissue specific binding proteins have been detected which could have their role in selection and maintenance of tissue specificity of promoters.
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Mishra, S., Mittal, B. An evidence of presence of DNA-binding proteins in selection of dystrophic gene promoter. Exp Mol Med 28, 131–134 (1996). https://doi.org/10.1038/emm.1996.20
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DOI: https://doi.org/10.1038/emm.1996.20