- RESEARCH HIGHLIGHT
Inhibiting Sec61-mediated protein translocation
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Nature Reviews Drug Discovery 22, 535 (2023)
doi: https://doi.org/10.1038/d41573-023-00086-w
References
Itskanov, S. et al. A common mechanism of Sec61 translocon inhibition by small molecules. Nat. Chem. Biol. https://doi.org/10.1038/s41589-023-01337-y (2023)
Rehan, S. et al. Signal peptide mimicry primes Sec61 for client-selective inhibition. Nat. Chem. Biol. https://doi.org/10.1038/s41589-023-01326-1 (2023)