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  • RESEARCH HIGHLIGHT

Two birds with one stone

  1. Akila Sridhar

    1. BMC Microbiology

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Since the 1960s, there has been a decline in the discovery of new antibiotics, particularly against Gram-negative bacteria. Increases in antibiotic resistance call for an urgent need to identify suitable candidates for broad-spectrum antibiotics with novel mechanisms of action (MoA).

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Nature Reviews Drug Discovery 19, 512 (2020)

doi: https://doi.org/10.1038/d41573-020-00118-9

This article originally appeared in Nat. Rev. Microbiol. (https://doi.org/10.1038/s41579-020-0401-4)

References

  1. Martin, J. K. II, et al. A dual-mechanism antibiotic kills Gram-negative bacteria and avoids drug resistance. Cell https://doi.org/10.1016/j.cell.2020.05.005 (2020)

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