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Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination

Cell Research volume 28, pages 383386 (2018) | Download Citation

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Acknowledgements

We thank members of Ji, Sha and Huang labs for helpful discussions. We are grateful to Dr Tian Chi (ShanghaiTech University) for excellent manuscript editing. This works is supported by the National Natural Science Foundation of China (81671516, U1302227, U1602224 and 31571534), the National Key R&D Program (2016YFA0500903, 2016YFA0503300, 2016YFA0101401 and and 2017YFA0103803) and Local Grants (SKLRM-K201502 and 2015FA037).

Author information

Author notes

    • Yiqiang Cui
    • , Yuyu Niu
    • , Jiankui Zhou
    •  & Yongchang Chen

    These four authors contributed equally to this work.

Affiliations

  1. State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, 101 Longmian Rd., Jiangning District, Nanjing, Jiangsu 211166, China

    • Yiqiang Cui
    • , Yiwei Cheng
    • , Bo Zheng
    • , Jiahao Sha
    •  & Xuejiang Guo
  2. Yunnan Key Laboratory of Primate Biomedicine Research; Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan 650500, China

    • Yuyu Niu
    • , Yongchang Chen
    • , Zongyong Ai
    • , Chu Chu
    • , Hong Wang
    •  & Weizhi Ji
  3. School of Life Science and Technology, ShanghaiTech University, 100 Haike Rd., Pudong New District, Shanghai 201210, China

    • Jiankui Zhou
    •  & Xingxu Huang
  4. Kunming Ennovate Institute of Bioscience, Kunming, Yunnan 650000, China

    • Yuyu Niu
    • , Yongchang Chen
    •  & Weizhi Ji
  5. Department of Laboratory Animal Science, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China

    • Shangang Li
    •  & Xuejin Chen

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Corresponding authors

Correspondence to Xuejiang Guo or Xingxu Huang or Weizhi Ji.

Supplementary information

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    Supplementary information, Figures

    Supplementary information, Figure S1–S11

  2. 2.

    Supplementary information, Tables

    Supplementary information, Table S1–S9

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    Supplementary information, Data S1–S10

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DOI

https://doi.org/10.1038/cr.2018.10

(Supplementary information is linked to the online version of the paper on the Cell Research website.)

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