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Immunotherapy for viral and fungal infections

Bone Marrow Transplantation volume 50, pages S51–S54 (2015)Cite this article

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Abstract

Allogenic stem cell transplantation (allo-SCT) represents the only curative option for several hematological malignancies. Due to a delayed and dysfunctional immunological recovery infectious complications and residual tumor cells following allo-SCT are still major causes of failure of this procedure. Here we discuss the most common infectious complications of allo-SCT and describe current and future strategies to prophylaxe or treat these complications using novel immunotherapeutic strategies.

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Acknowledgements

Research Funds were received for this project by EU FP7 T-Control and the Deutsche Forschungsgemeinschaft (DFG) CRC/TR 124.

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Authors and Affiliations

  1. Department of Internal Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany

    H Einsele, J Löffler, M Kapp, L Rasche, S Mielke & U G Grigoleit

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  1. H Einsele
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  2. J Löffler
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  3. M Kapp
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  4. L Rasche
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  5. S Mielke
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  6. U G Grigoleit
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Correspondence to H Einsele.

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Competing interests

HE received consulting and lecture fees from Celgene, Janssen, Amgen, Onyx and Novartis. JL received grant support from Pfizer Europe. SM has received lecture fees from Deutschen Rentenversicherung, Cellex GmbH, Novartis Pharma, Shire, and grant support from Wilhelm-Sander-Stiftunq. Germany, Carreras-Leukamie-Stiftunq. The remaining authors declare no conflict of interest.

Additional information

This article was published as part of a supplement, supported by WIS-CSP Foundation, in collaboration with Gilead, Milteny Biotec, Gamida cell, Adienne Pharma and Biotech, Medac hematology, Kiadis Pharma, Almog Diagnostic.

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Einsele, H., Löffler, J., Kapp, M. et al. Immunotherapy for viral and fungal infections. Bone Marrow Transplant 50 (Suppl 2), S51–S54 (2015). https://doi.org/10.1038/bmt.2015.96

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