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Linear IgA bullous dermatosis following autologous PBSC transplantation in a patient with non-Hodgkin's lymphoma

Bone Marrow Transplantation volume 46, pages 156–158 (2011)Cite this article

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Autoimmune mucocutaneous blistering diseases (AMBDs) are rare but potentially life-threatening complications after hematopoietic SCT (HSCT). Linear IgA bullous dermatosis (LABD) is one type of AMBD, and clinically resembles bullous pemphigoid, dermatitis herpetiformis, cicatrical pemphigoid and pemphigus vulgaris.1, 2, 3 It is histologically characterized by linear deposits of IgA at the basement membrane zone in immunofluorescent studies, and is usually provoked by infections, drugs or malignancies, especially lymphoproliferative disorders.1, 3, 4

Here, we describe a patient with non-Hodgkin's lymphoma who developed LABD after autologous HSCT and was successfully treated with glucocorticoid, dapsone and high-dose i.v. Ig, but the lymphoma recurred in a short period of time.

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Acknowledgements

This study was supported by a grant from the National R&D Program for Cancer Control, Ministry of Health & Welfare, Republic of Korea (0620220-1).

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Authors and Affiliations

  1. Division of Hematology/Oncology, Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea

    H Y Yhim, D H Kwon, N R Lee, E K Song, C Y Yim & J Y Kwak

  2. Advanced Research Cancer Center, Chonbuk National University Medical School, Jeonju, Korea

    N R Lee, E K Song, C Y Yim & J Y Kwak

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  1. H Y Yhim
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  2. D H Kwon
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Correspondence to J Y Kwak.

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Yhim, H., Kwon, D., Lee, N. et al. Linear IgA bullous dermatosis following autologous PBSC transplantation in a patient with non-Hodgkin's lymphoma. Bone Marrow Transplant 46, 156–158 (2011). https://doi.org/10.1038/bmt.2010.73

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