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Haematopoietic stem cell donor registries: World Marrow Donor Association recommendations for evaluation of donor health

Bone Marrow Transplantation volume 42, pages 9–14 (2008)Cite this article

Abstract

The ability to identify unrelated haematopoietic stem cell donors in one country for recipients in another country requires cooperation and standardization in many areas. The donor assessment and testing are very important issues affecting quality and safety of donation. This special report details the World Marrow Donor Association's recommended procedures regarding the medical evaluation of donors, with the intent to protect the volunteer from the risk to damage his health and to offer the recipient the appropriate quality of stem cells. This document describes criteria for permanent or temporary deferral, guidelines for risk evaluation of infectious disease, examples of conditions requiring assessment and questionnaires designed to elicit relevant information about a donor's medical history and general health.

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References

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Acknowledgements

We thank the WMDA members for their contributions and the WMDA Board for review of this paper.

Author information

Authors and Affiliations

  1. Italian Bone Marrow Donor Registry, Genova, Italy

    N Sacchi

  2. The Cyprus Bone Marrow Donor Registry, Nicosia, Cyprus

    P Costeas

  3. The Anthony Nolan Bone Marrow Trust, London, UK

    L Hartwell

  4. Department of Oncology, Georgetown University Medical School, Washington, DC, USA

    C K Hurley

  5. France Greffe de Moelle, Paris, France

    C Raffoux

  6. Austrian Bone Marrow Donor Registry, Vienna, Austria

    A Rosenmayr

  7. Department of Internal Medicine I, Bone Marrow Transplantation, Medical University of Vienna, Vienna, Austria

    H Greinix

Authors
  1. N Sacchi
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  2. P Costeas
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  3. L Hartwell
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  4. C K Hurley
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  5. C Raffoux
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  6. A Rosenmayr
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  7. H Greinix
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Consortia

on behalf of the Quality Assurance and Clinical Working Groups of the World Marrow Donor Association

Corresponding author

Correspondence to N Sacchi.

Appendices

Appendix 1

Donor health questionnaire before the first registration

Appendix 2

Donor health questionnaire at time of closer consideration for a certain patient (confirmatory typing or work up)

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Sacchi, N., Costeas, P., Hartwell, L. et al. Haematopoietic stem cell donor registries: World Marrow Donor Association recommendations for evaluation of donor health. Bone Marrow Transplant 42, 9–14 (2008). https://doi.org/10.1038/bmt.2008.76

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  • DOI: https://doi.org/10.1038/bmt.2008.76

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