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Infectious Diseases

Invasive mycoses in children receiving hemopoietic SCT

Bone Marrow Transplantation volume 41, pages S107–S111 (2008)Cite this article

Abstract

Invasive mycoses represent a rare but severe complication following hemopoietic SCT (HSCT) in children. Their incidence is related to the type of donor, being higher after allogeneic transplant, especially from alternative donors. Moreover, the incidence of invasive mycoses varies in the different post transplant phases. Neutropenia, lymphopenia, GvHD, high-dose steroids or other immunosuppressive drugs represent well-known risk factors. The clinical features of invasive mycoses after HSCT in children are similar to those observed in adults, and the diagnostic tools, including Aspergillus galactomannan antigen detection, are feasible also in pediatrics. Mortality due to invasive mycoses after HSCT in children is high.

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Authors and Affiliations

  1. Department of Hematology and Oncology, Infectious Diseases Unit, G. Gaslini Children Hospital, Genoa, Italy

    E Castagnola, I Caviglia & A R Natalizia

  2. Bone Marrow Transplant Unit, G. Gaslini Children Hospital, Genoa, Italy

    M Faraci, V de Fazio, G Morreale, E Lanino & G Dini

  3. Laboratory of Microbiology, G. Gaslini Children Hospital, Genoa, Italy

    C Moroni & R Bandettini

  4. Service of Radiology, G. Gaslini Children Hospital, Genoa, Italy

    C Granata

  5. Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Children Hospital, Genoa, Italy

    S Caruso, F Bagnasco & R Haupt

  6. Division of Infectious Diseases, Department of Hematology and Oncology, San Martino University Hospital, University of Genoa, Genoa, Italy

    M Malgorzata, E Furfaro & C Viscoli

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  1. E Castagnola
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Correspondence to E Castagnola.

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Castagnola, E., Faraci, M., Moroni, C. et al. Invasive mycoses in children receiving hemopoietic SCT. Bone Marrow Transplant 41 (Suppl 2), S107–S111 (2008). https://doi.org/10.1038/bmt.2008.67

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