Abstract
In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude mice. The tumours formed by the annexin VI+ A431 cells were morphologically and histologically similar to those formed by the wild-type cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 24 print issues and online access
$259.00 per year
only $10.79 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Theobald, J., Hanby, A., Patel, K. et al. Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells. Br J Cancer 71, 786–788 (1995). https://doi.org/10.1038/bjc.1995.152
Issue Date:
DOI: https://doi.org/10.1038/bjc.1995.152
This article is cited by
-
Annexin A6 is a scaffold for PKCα to promote EGFR inactivation
Oncogene (2013)
-
Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity
Oncogene (2005)
-
Annexin V inhibits the 12-O-tetradecanoylphorbol-13-acetate-induced activation of Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of Shc in MCF-7 cells
Oncogene (2000)
-
Gene expression profiling of fibroblasts resistant toward oncogene-mediated transformation reveals preferential transcription of negative growth regulators
Oncogene (1999)
