Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Experimental Oncology
  • Published:

Preferentially expressed genes in stomach adenocarcinoma cells

British Journal of Cancer volume 56, pages 539–544 (1987)Cite this article

Abstract

cDNA clones complementary to mRNA of neoplastic cells of human stomach tissue were used to examine quantitative changes in the mRNA levels of specific genes in neoplastic cells. Poly(A)+ RNA from poorly differentiated adenocarcinoma cells of a female patient with stomach cancer was used for construction of a complementary DNA (cDNA) library. Screening of the 18,000 colonies utilizing 32P-cDNAs derived from normal human tissue and stomach carcinoma tissue samples was used to select clones likely to represent sequences preferentially expressed in stomach carcinoma cells. Twenty-six recombinants were initially selected and further analysis of these clones indicated that eight (4-3D, 9-2D, 9-4G, 29-1G, 29-6F, 37-1B, 115-5A and 52-5F) contain sequences preferentially expressed in stomach carcinoma cells. We have identified the 9-4G, 29-1A, and 29-6F genes which are differentially expressed in human neoplasia.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

Author information

Authors and Affiliations

  1. First Department of Internal Medicine, School of Medicine, Ehime University, Japan

    T Shiosaka

Authors
  1. T Shiosaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Y Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y Kobayashi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shiosaka, T., Tanaka, Y. & Kobayashi, Y. Preferentially expressed genes in stomach adenocarcinoma cells. Br J Cancer 56, 539–544 (1987). https://doi.org/10.1038/bjc.1987.239

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/bjc.1987.239

This article is cited by

Search

Advanced search

Quick links