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Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen

British Journal of Cancer volume 40, pages 608–614 (1979)Cite this article

Abstract

The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded 2 cm. Cattle with aquamous-cell carcinomas had cell-mediated immunity against tumour extracts, as measured by the leucocyte adherence inhibition (LAI) microassay. The LAI reaction against tumour extracts was directly proportional to the general level of cell-mediated immunity as demonstrated by the lymphoproliferative response to PHA.

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Authors
  1. P A Jennings
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  2. M F Lavin
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  3. D J Hughes
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  4. P B Spradbrow
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Jennings, P., Lavin, M., Hughes, D. et al. Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen. Br J Cancer 40, 608–614 (1979). https://doi.org/10.1038/bjc.1979.226

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  • DOI: https://doi.org/10.1038/bjc.1979.226

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