Abstract
Explants of lung from 1 month old inbred BALB/c mice were cultured in vitro for 4 days with 3-methylcholanthrene added to the culture medium at various dose levels. They were subsequently implanted subcutaneously into 6-week-old mice of the same strain.
Lung adenomata appeared in a high proportion of explants.
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Davies, R., Major, I. & Aberdeen, E. Pulmonary Adenomata Induced by Carcinogen Treatment in Organ Culture. Influence of Increasing Amounts of Carcinogen. Br J Cancer 24, 785–787 (1970). https://doi.org/10.1038/bjc.1970.93
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DOI: https://doi.org/10.1038/bjc.1970.93