Main

Griffin SO, Regnier E et al. J Dent Res 2007; 86: 410–415

The authors note that no previous systematic reviews had found fluoride effective in preventing adult caries. From an initial 489 articles identified, 50 were reviewed against specific criteria, and finally 20 were included in the analysis.

Studies included fluoride delivery by water supply, mouthrinses, dentifrices and professional application. Analysis of annual coronal caries increments gave a difference of 0.64 surfaces (P < 0.05) for a total of 11 studies with 4,809 participants. In 5 studies of root caries with 1894 participants, annual difference was 0.22 (P < 0.05). Lifetime exposure to fluoride in water gave a figure of 35% prevention of caries.