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Gold nanoparticles in cancer therapy

Acta Pharmacologica Sinica volume 32, pages 983990 (2011) | Download Citation

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Abstract

The rapid advancement of nanotechnology in recent years has fuelled a burgeoning interest in the field of nanoparticle research, in particular, its application in the medical arena. A constantly expanding knowledge based on a better understanding of the properties of gold nanoparticles (AuNPs) coupled with relentless experimentation means that the frontiers of nanotechnology are constantly being challenged. At present, there seems to be heightened interest in the application of AuNPs to the management of cancer, encompassing diagnosis, monitoring and treatment of the disease. These efforts are undertaken in the hope of revolutionizing current methods of treatment and treatment strategies for a multifactorial disease such as cancer. This review will focus on the current applications of AuNPs in cancer management.

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Acknowledgements

The authors are grateful to Song-Lin BAY for her assistance in preparing the figures. This work was supported by research funding from the Singapore Ministry of Education Academic Research Fund Tier 1 via grant R279-000-205-112 and Tier 2 via grant MOE2008-T2-1-046, and the National University of Singapore Environmental Research Institute (NERI) via grant R706-000-002-646.

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Affiliations

  1. Department of Anatomy, National University of Singapore, Singapore;

    • Zhao-Zhin Joanna Lim
    • , Jia-En Jasmine Li
    • , Cheng-Teng Ng
    •  & Boon-Huat Bay
  2. Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore

    • Jia-En Jasmine Li
    • , Cheng-Teng Ng
    •  & Lin-Yue Lanry Yung

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Corresponding authors

Correspondence to Lin-Yue Lanry Yung or Boon-Huat Bay.

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DOI

https://doi.org/10.1038/aps.2011.82

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