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The ECETOC approach to targeted risk assessment; lessons and experiences relevant to REACH

Journal of Exposure Science & Environmental Epidemiology volume 17, pages S67–S71 (2007)Cite this article

Abstract

ECETOC has been developed an approach by which the health and environmental risks arising from the supply and use of chemicals can be quickly and reliably evaluated by chemical suppliers. The approach has been available as a web-based tool since 2004. During the development and implementation of the approach, ECETOC has consulted widely so that the approach is seen to meet the required levels of science while also meeting the differing needs of affected stakeholders. The consultation process has yielded a number of findings in terms of the considerations necessary for implementing successful risk-informed decision-making in a multi-stakeholder environment. Concurrently, as the European Commission's REACH legislative package has begun to take shape, it has also become apparent that the approach has a number of potential applications for aiding the process of risk assessment under REACH. This paper reviews these experiences within the broader context of the expectations that REACH places on chemical manufacturers and suppliers. In particular, it highlights the key role that REACH Exposure Scenarios have for evaluating, managing and communicating chemical risks.

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References

  • Barlow S.M., Kozianowsky G., Würtzen G., and Schlatter J. Threshold of toxicological concern for chemical substances present in diet. Food Chem Toxicol (2001): 39: 893–905.

    Article  CAS  Google Scholar 

  • Briggs D., and Crumbie N. Characteristics of People Working With Chemical Products in Small Firms, Health & Safety Executive Contract Research Report 278, HMSO, Norwich, (2000).

    Google Scholar 

  • Brooke I.M. A UK Scheme to Help Small Firms Control Health Risks from Chemicals: Toxicological Considerations. Ann Occup Hyg (1998): 42: 377–390.

    Article  CAS  Google Scholar 

  • CIA. Safe Handling of Colourants 2. Chemical Industries Association, London, (1993).

  • Creely K.S., Tickner J., Soutar A.J., Hughson G.W., Pryde D.E., Warren N.D., Rae R., Money C., Phillips A., and Cherrie J.W. Evaluation and further development of EASE model 2.0. Ann Occup Hyg (2005): 49: 135–145.

    CAS  PubMed  Google Scholar 

  • ECETOC. Targeted Risk Assessment, Technical Report No. 93, European Centre for the Ecotoxicology and Toxicology of Chemicals, Brussels, (2004).

  • European Commission. White Paper on the Strategy for a Future Chemicals Policy. Document COM(2001)88, Brussels, (2001).

  • European Commission. Proposal for a Regulation of the European Parliament and of the Council Concerning the Registration. Evaluation, Authorisation and Restriction of Chemicals (Reach) Document (COM(03) 644 (01)), Brussels, (2003).

  • Guest I. The Chemical Industries Association Guidance on Allocating Occupational Exposure Bands. Ann Occup Hyg (1998): 42: 407–411.

    Article  CAS  Google Scholar 

  • HERA. Five years ahead of REACH. European Voice (2005): 11 (13).

  • JRC. RIP 3.2-1 Scoping report. Technical Guidance Document on preparing the Chemical Safety Report under REACH – Scoping Study – Phase 1 A (REACH Implementation Project 3.2-1A) Service Contract Number 22551-2004-12 F1SC ISP BE, EU Joint Research Centre, Ispra, (2005).

  • Kroes R., Galli C., Munro I., Schilter B., Tran L-A., Walzer R., and Würtzen G. Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing. Food Chem Toxicol (2000): 34: 829–867.

    Google Scholar 

  • Maidment S.C. Occupational hygiene considerations in the development of a structured approach to select chemical control strategies. Ann Occup Hyg Hygiene (1998): 42: 391–400.

    Article  CAS  Google Scholar 

  • McKee R.H., Medeiros A.M., and Daughtrey W.C. A proposed methodology for setting occupational exposure limits for hydrocarbon solvents. J Occup Environ Hyg (2005): 2: 524–542.

    Article  CAS  Google Scholar 

  • Money C. European approaches in the development of approaches for the successful control of workplace health risks. Ann Occup Hyg (2003): 47: 533–540.

    CAS  PubMed  Google Scholar 

  • Money C., de Rooij C., Floch F., Jacobi S., Koundakjian P., Lanz S., Penman M., Rodriguez C., and Veenstra G. A structured approach to the evaluation of workplace health risks'. Policy and Practice in Health and Safety (2003): 2: 44–65.

    Google Scholar 

  • Naumann B.D., Sargent E.V., Starkman B.S., Fraser W.J., Becker G.T., and Kirk G.D. Performance-based exposure control limits for pharmaceutical active ingredients. Am Ind Hyg Assoc J (1996): 57: 33–42.

    Article  CAS  Google Scholar 

  • O'Hara J., Williamson J., Benjamin K., Marlow P., White J., and Wright S. E-COSHH Essentials Guidance Sheets: User Consultation Exercise, Health and Safety Laboratory Report RAS/03/10, HSL, Sheffield., (2003).

    Google Scholar 

  • Schneider T., Vermeulen R., Brouwer D., Cherrie J., Kromhout H., and Fogh C. A conceptual model for assessment of dermal exposure. Occup and Environ Med (1999): 56: 765–773.

    Article  CAS  Google Scholar 

  • Verdonck F.A.M., Boije G., Vandenberghe V., Comber M., de Wolf W., Feijtel T., Holt M., Koch V., Lecloux A., Sibel-Sauer A., and Vanrolleghem P.A. A rule-based screening environmental risk assessment tool derived from EUSES. Chemosphere (2005): 58: 1169–1176.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. ExxonMobil, Machelen, Belgium

    Chris D Money

  2. Albemarle, Louvain-la-Neuve, Belgium

    Sylvia Jacobi

  3. ExxonMobil Biomedical Sciences, Machelen, Belgium

    Mike G Penman

  4. Procter & Gamble, Strombeek-Bever, Belgium

    Carlos Rodriguez

  5. Consultant, Amsterdam, Netherlands

    Christ De Rooij

  6. Shell International, The Hague, Netherlands

    Gauke Veenstra

Authors
  1. Chris D Money
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  2. Sylvia Jacobi
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  3. Mike G Penman
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  4. Carlos Rodriguez
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  5. Christ De Rooij
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  6. Gauke Veenstra
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Correspondence to Chris D Money.

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Money, C., Jacobi, S., Penman, M. et al. The ECETOC approach to targeted risk assessment; lessons and experiences relevant to REACH. J Expo Sci Environ Epidemiol 17 (Suppl 1), S67–S71 (2007). https://doi.org/10.1038/sj.jes.7500565

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