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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Fatal influenza B virus pneumonia in a preterm neonate: case report and review of the literature

Abstract

Although less common than influenza A, influenza B infections can cause significant mortality and morbidity in children who are immunocomprised and have underlying medical conditions. We report a preterm neonate with fatal influenza B virus pneumonia. This infant presented with signs and symptoms indistinguishable from any other cause of sepsis.

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References

  1. American Academy of Pediatrics. Influenza. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th edn. American Academy of Pediatrics: Elk Grove Village, IL, 2006.

  2. Healy CM, Baker CJ . Prospects for prevention of childhood infections by maternal immunizations. Curr Opin Infect Dis 2006; 19: 271–276.

    Article  Google Scholar 

  3. Wilkinson DJ, Buttery JP, CC A . Influenza in the neonatal intensive care unit. J Perinatol 2006; 26: 772–776.

    Article  CAS  Google Scholar 

  4. Liou YS, Barbour SD, Bell LM, Plotkin SA . Children hospitalized with influenza B infection. Pediatr Infect Dis J 1987; 6(6): 541–543.

    Article  CAS  Google Scholar 

  5. Meibalane R, Sedmak GV, Sasidharan P, Garg P, Grausz JP . Outbreak of influenza in a neonatal intensive care unit. J Pediatr 1977; 91(6): 974–976.

    Article  CAS  Google Scholar 

  6. Cunney RJ, Bialachowski A, Thornley D, Smaill FM, Pennie RA . An outbreak of influenza A in a neonatal intensive care unit. Infect Control Hosp Epidemiol 2000; 21: 449–454.

    Article  CAS  Google Scholar 

  7. van den Dungen FA, van Furth AM, Fetter WP, Zaaijer HL, van Elburg RM . Fatal case of influenza B virus pneumonia in a preterm neonate. Pediatr Infect Dis J 2001; 20(1): 82–84.

    Article  CAS  Google Scholar 

  8. Guarner J, Paddock CD, Shieh WJ, Packard MM, Patel M, Montague JL et al. Histopathologic and immunohistochemical features of fatal influenza virus infection in children during the 2003–2004 season. Clin Infect Dis 2006; 43: 132–140.

    Article  Google Scholar 

  9. Troendle JF, Demmler GJ, Glezen WP, Finegold M, Romano MJ . Fatal influenza B virus pneumonia in pediatric patients. Pediatr Infect Dis J 1992; 11(2): 117–121.

    Article  CAS  Google Scholar 

  10. Weigl JAI, Puppe W, Schmitt HJ . The incidence of influenza-associated hospitalizations in children in Germany. Epidemiol Infect 2002; 129(3): 525–533.

    Article  CAS  Google Scholar 

  11. Quach C, Piche-Walker L, Platt R, Moore D . Risk factors associated with severe influenza infections in childhood: implication for vaccine strategy. Pediatrics 2003; 112: e197–e201.

    Article  Google Scholar 

  12. Vieira RA, Diniz EM, Vaz FA . Clinical and laboratory study of newborns with lower respiratory tract infection due to respiratory viruses. J Matern-Fetal Neonatal Med 2003; 13(5): 341–350.

    Article  CAS  Google Scholar 

  13. Uyeki TM . Influenza diagnosis and treatment in children: a review of studies on clinically useful tests and antiviral treatment for influenza. Pediatr Infect Dis J 2003; 22: 164–177.

    PubMed  Google Scholar 

  14. Kuypers J, Wright N, Ferrenberg J, Huang ML, Cent A, Corey L et al. Comparison of real-time PCR assays with fluoroscent-antibody assays for diagnosis of respiratory virus infections in children. J Clin Microbiol 2006; 44(7): 2382–2388.

    Article  CAS  Google Scholar 

  15. Moore C, Hibbitts S, Owen N, Corden SA, Harrison G, Fox J et al. Development and evaluation of a real-time nucleic acid sequence based amplification assay for rapid detection of influenza A. J Med Virol 2004; 74: 619–628.

    Article  CAS  Google Scholar 

  16. Public Health Agency of Canada. Influenza in Canada-2004–2005 season. Can Commun Dis Rep 2006; 32: 57–76.

  17. Shah S, Capro M . Optimizing long-term care by administration of influenza vaccine to parents of NICU patients. J Perinatol 2004; 24: 273–274.

    Article  Google Scholar 

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Correspondence to K Yusuf.

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Yusuf, K., Soraisham, A. & Fonseca, K. Fatal influenza B virus pneumonia in a preterm neonate: case report and review of the literature. J Perinatol 27, 623–625 (2007). https://doi.org/10.1038/sj.jp.7211802

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