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  • Perinatal/Neonatal Case Presentation
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Perinatal/Neonatal Case Presentation

Neonatal anemia and hydrops fetalis after maternal mycophenolate mofetil use

Abstract

After admitting a patient to our Neonatal Intensive Care with a severe anemia and an ear malformation, we ruled out any other cause than maternal medication use. Knowing she used mycophenolate mofetil during pregnancy, we looked for related articles. Two articles were found describing ear malformations, but no article was ever written about anemia caused by this medication. Consulting the international registers of drug effects through the National Institute for Public Health and the Environment, we found out that the anemia was never seen or reported before.

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  1. Pergola PE, Kancharia A, Riley DJ . Kidney transplantation during the first trimester of pregnancy: immunosuppression with mycophenolate mofetil, tacrolimus, and prednisone. Transplantation 2001; 71 (7): 994–997. Review.

    Article  CAS  Google Scholar 

  2. Magee LA, Mazzotta P, Koren G . Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP). Am J Obstet Gynecol 2002; 196: S256–S261.

    Article  Google Scholar 

  3. McKenna K, Koren G, Tetelbaum M, Wilton L, Shakir S, Diav-Citrin O, Levinson A, Zipursky RB, Einarson A . Pregnancy outcome of women using atypical antipsychotic drugs: a prospective comparative study. J Clin Psychiatry 2005; 66 (4): 444–449; quiz 546.

    Article  CAS  Google Scholar 

  4. Le Ray C, Coulomb A, Elefant E, Frydman R, Audibert F . Mycophenolate Mofetil in pregnancy after renal transplantation: a case of major fetal malformations. Obstet Gynaecol 2004; 103 (5 Part 2): 1091–1094.

    Article  Google Scholar 

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Correspondence to I F A Tjeertes.

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Tjeertes, I., Bastiaans, D., van Ganzewinkel, C. et al. Neonatal anemia and hydrops fetalis after maternal mycophenolate mofetil use. J Perinatol 27, 62–64 (2007). https://doi.org/10.1038/sj.jp.7211631

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  • DOI: https://doi.org/10.1038/sj.jp.7211631

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