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ABO Incompatibility, Response to Dr. Birenbaum

Journal of Perinatology volume 25, page 806 (2005)Cite this article

We greatly appreciate Dr. Birenbaum's interest and comments on our study of prophylactic phototherapy in ABO incompatibility. In fact, measuring total serum bilirubin (TSB) for infants without ABO incompatibility is not routinely performed in our unit. Instead of that, we found a benefit in comparing between two groups of ABO incompatible neonates, the first group includes neonates who had positive direct Coomb's test (DCT) (n=242) and the second with negative DCT (n=851). If we accept that infants with negative DCT have no significant hemolysis, such comparative analysis would, perhaps partially, answer the first enquiry of Dr. Birenbaum.

In revising our data, we found that neonates with positive DCT had significantly more reticulocytes with mean of 7.3±4.4 versus 5.5%±3.6% in negative DCT infants (P<0.0001).

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Authors and Affiliations

  1. AL Qassimi Hospital, Sharjah, UAE

    Hakam Yaseen MD, CES, DUN, FRCPCH, Mona Khalaf MRCP, Najat Rashid PhD & Maha Darwich MD, CES

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  1. Hakam Yaseen MD, CES, DUN, FRCPCH
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  2. Mona Khalaf MRCP
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  3. Najat Rashid PhD
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  4. Maha Darwich MD, CES
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Yaseen, H., Khalaf, M., Rashid, N. et al. ABO Incompatibility, Response to Dr. Birenbaum. J Perinatol 25, 806 (2005). https://doi.org/10.1038/sj.jp.7211400

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