Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Clinical/Perinatal Neonatal Case Presentation
  • Published:

Clinical Perinatal/Neonatal Case Presentation

Candida Chorioamnionitis After Serial Therapeutic Amniocenteses: A Possible Association

Journal of Perinatology volume 20, pages 335–337 (2000)Cite this article

Abstract

BACKGROUND: Reduction amniocentesis is used in cases of severe polyhydramnios to decrease maternal discomfort and the risk of preterm labor. In a MEDLINE search (1966 to present, English language, keywords: amniocentesis, chorioamnionitis), no report of Candida chorioamnionitis after serial reduction amniocentesis exists.

CASE:

A 29-year-old primigravida with a history of four therapeutic amniocenteses for idiopathic polyhydramnios developed preterm labor at 30 and 5/7 weeks’ gestation, rupture of membranes, and Candida albicans chorioamnionitis. Despite aggressive therapy with amphotericin B, the neonate succumbed to overwhelming systemic candidiasis.

CONCLUSION: Serial amniocentesis may place patients at elevated risk for Candida chorioamnionitis and subsequent preterm delivery. Clinicians should consider early diagnostic amniocentesis in patients in preterm labor with a history of prior amniocentesis, and the routine Gram stain and culture of amniotic fluid.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Division of Maternal-Fetal Medicine (M. E. R., Department of Obstetrics and Gynecology, M. A. M., I. F.), The University of Pennsylvania Health System, Philadelphia, PA

    Martha E Rode MD, Mark A Morgan MD & Iraj Forouzan MD

  2. Department of Pathology (E. R.), The Children’s Hospital of Philadelphia, Philadelphia, PA

    Eduardo Ruchelli MD

Authors
  1. Martha E Rode MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mark A Morgan MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eduardo Ruchelli MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Iraj Forouzan MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Martha E Rode MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rode, M., Morgan, M., Ruchelli, E. et al. Candida Chorioamnionitis After Serial Therapeutic Amniocenteses: A Possible Association. J Perinatol 20, 335–337 (2000). https://doi.org/10.1038/sj.jp.7200381

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.jp.7200381

This article is cited by

Search

Advanced search

Quick links