Abstract
Question: Do hydroxyapatite implants last as long as titanium implants?
Objective Identify and critically review human clinical trials that examined the survival of hydroxyapatite-coated implants.
Data sources Medline (1990–1999) was searched using the keywords ‘hydroxyapatite’ or ‘hydroxylapatite’.
Study selection Papers were included that were written in English and met the criteria that they: included at least 10 patients; at least a 6-month follow-up; no more than 5% loss-from-study of patients; overall implant survival reported by overall percentage-survival or by life-table analysis; and no barrier membranes were used.
Data extraction Cumulative life-table survival curves were presented from the included studies. No attempts at synthesis or pooling the data were made.
Results Out of 45 papers identified, 34 were excluded due to various deficiencies. Eleven studies met the criteria, representing some 14000 implants. Only one study was a randomised controlled trial (RCT). The estimated survival rates vary between 79% for IMZ* to 96% for Steri-Oss# at 8 years, 93% for Sterngold/Implamed¥ at 3 years and 98% for integral at 4 years.
Conclusion The authors suggest that the survival rates for the hydroxyapatite-coated implants are in the same range as the survival rates for titanium implants. More information is required, however, including better quality clinical studies and reporting.
*IMZ–Interpore International, Irvine CA
#Steri-Oss–Yorba Linda, CA
¥Sterngold/implamed–Attenboro, MA
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Address for reprints: Dr Beirne, Department of Oral and Maxillofacial Surgery, University of Washington, Box 357134, Seattle WA 98195–7134, USA.
Lee JJ, Rouhfar L, Beirne OR. Survival of hydroxyapatite-coated implants: a meta-analytic review. J Oral Maxil Surg 2000; 58: 1372–1379
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Creugers, N. The survival of hydroxyapatite-coated implants is questioned. Evid Based Dent 3, 77–78 (2002). https://doi.org/10.1038/sj.ebd.6400129
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DOI: https://doi.org/10.1038/sj.ebd.6400129
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