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A bi-allelic VNTR in the human TNFR2 (p75) gene promoter

Genes & Immunity volume 1, pages 164–165 (1999)Cite this article

Abstract

We describe a bi-allelic VNTR polymorphism within a 42 bp region in the promoter of the tumour necrosis factor receptor 2 gene (TNFR2). Within this region there are one (Allele 1) or two (Allele 2) repeats of a 15 bp sequence, 5′-GCCGGGC AGGTGGAG-3′. Allele frequencies observed in a Caucasian population were 0.3 (Allele 1) and 0.7 (Allele 2).

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Authors and Affiliations

  1. Division of Transplantation Sciences, University of Bristol, Homoeopathic Hospital Site, Cotham, Bristol, BS6 6JU, UK

    L Keen

  2. Department of Pathology and Microbiology, University of Bristol, Homoeopathic Hospital Site, Cotham, Bristol, BS6 6JU, UK

    N Wood, O Olomolaiye & J Bidwell

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  1. L Keen
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  2. N Wood
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  3. O Olomolaiye
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  4. J Bidwell
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Correspondence to L Keen.

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Keen, L., Wood, N., Olomolaiye, O. et al. A bi-allelic VNTR in the human TNFR2 (p75) gene promoter. Genes Immun 1, 164–165 (1999). https://doi.org/10.1038/sj.gene.6363644

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  • DOI: https://doi.org/10.1038/sj.gene.6363644

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