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Abstract
The effect was greater than that of a fluoride toothpaste and may account for a reduction in halitosis.
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Sreenivasan P Eur J Oral Sci 2003; 111: 223–227
A crossover trial was performed in 20 subjects using a fluoride dentifrice containing 0.3% triclosan in the copolymer formulation, and a traditional fluoride dentifrice as negative control. For 7 days, the control was used by all subjects, salivary microbial samples were taken, and subjects were randomized to test or control dentifrice for 7 days, when more samples were taken before and 2 hrs and 4 hrs after brushing. Subjects then used the other toothpaste for 7 days and were sampled similarly.
There were moderate significant reductions of all bacteria in CFU/ ml of saliva in the 3 samples taken after dentifrice use. When sulfide-producing bacteria were examined, they too showed a significant decrease. The authors note that a previous study using the organoleptic method of assessment (human noses rather than industrial sulfide monitors) showed a decrease in halitosis after using a triclosan-copolymer dentifrice, and suggest that their findings account for the effect.
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The effects of a triclosan/copolymer dentifrice on oral bacteria including those producing hydrogen sulfide. Br Dent J 195, 143 (2003). https://doi.org/10.1038/sj.bdj.4810397
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DOI: https://doi.org/10.1038/sj.bdj.4810397