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Opiate drugs: ‘guilt by association’

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References

  1. Duttaroy A, Yoburn BC . The effect of intrinsic efficacy on opioid tolerance Anesthesiology 1995; 82: 1226–1236

    Article  CAS  Google Scholar 

  2. Walsh SL, Preston KL, Stitzer ML, Cone EJ, Bigelow GE . Clinical pharmacology of buprenorphine: ceiling effects at high doses Clin Pharmacol Ther 1994; 55: 569–580

    Article  CAS  Google Scholar 

  3. Ling W, Rawson RA, Compton MA . Substitution pharmacotherapies for opioid addiction: from methadone to LAAM and buprenorphine J Psychoactive Drugs 1994; 26: 119–128

    Article  CAS  Google Scholar 

  4. Massotte D, Kieffer BL . A molecular basis for opiate action Essays Biochem 1998; 33: 65–77

    Article  CAS  Google Scholar 

  5. Zaki PA, Keith DE Jr, Brine GA, Carroll FI, Evans CJ . The role of G protein activation in agonist-dependent mu-opioid receptor internalization JPET 2000; 292: (in press)

  6. Yin X, Sun H, Uhl GR, Wang JB . Mu opioid receptor phosphorylation, desensitization, and ligand efficacy J Biol Chem 1997; 272: 28869–28874

    Article  Google Scholar 

  7. Keith DE, Anton B, Murray SR, Zaki PA, Chu PC, Lissin DV et al. mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain Mol Pharmacol 1998; 53: 377–384

    Article  CAS  Google Scholar 

  8. Bodkin JA, Zornberg GL, Lukas SE, Cole JO . Buprenorphine treatment of refractory depression J Clin Psychopharmacol 1995; 15: 49–57

    Article  CAS  Google Scholar 

  9. Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B et al. Cocaine self-administration in dopamine-transporter knockout mice Nat Neurosci 1998; 1: 132–137

    Article  CAS  Google Scholar 

Download references

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Correspondence to C J Evans.

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Evans, C., Monteillet-Agius, G., Saliminejad, N. et al. Opiate drugs: ‘guilt by association’. Mol Psychiatry 5, 122–123 (2000). https://doi.org/10.1038/sj.mp.4000739

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