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An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

Molecular Psychiatry volume 3, pages 449–451 (1998)Cite this article

Abstract

A functional polymorphism in the regulatory region of the serotonin transporter gene has been reported to be associated with anxiety-related personality traits.1 We attempted to replicate this finding in an association study involving 759 Caucasians selected from the general Australian population. We found no associations with personality traits (including neuroticism, negative affect and behavioral inhibition), anxiety and depressive symptoms, or alcohol misuse.

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Authors and Affiliations

  1. NHMRC Psychiatric Epidemiology Research Centre, The Australian National University, Canberra, 0200, Australia

    A F Jorm, A S Henderson, P A Jacomb, H Christensen, A E Korten & B Rodgers

  2. John Curtin School of Medical Research, Australian National University, Canberra, 0200, Australia

    X Tan & S Easteal

Authors
  1. A F Jorm
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  2. A S Henderson
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  3. P A Jacomb
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  4. H Christensen
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  5. A E Korten
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  6. B Rodgers
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  7. X Tan
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  8. S Easteal
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Correspondence to A F Jorm.

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Jorm, A., Henderson, A., Jacomb, P. et al. An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms. Mol Psychiatry 3, 449–451 (1998). https://doi.org/10.1038/sj.mp.4000424

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  • DOI: https://doi.org/10.1038/sj.mp.4000424

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