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The D2 receptor: love it and leave it

Molecular Psychiatry volume 3, pages 101–102 (1998)Cite this article

Abstract

Occupancy of the D2 receptor has been a foundation for the mechanism of antipsychotic action for over two decades. The introduction of atypical antipsychotics and their multiple receptor profiles coupled with functional brain imaging technology has raised questions about what once was considered to be a very tight concept. We address controversial facets to the D2 receptor's involvement in the antipsychotic mechanism and point to future clinical research directions.

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  1. Experimental Therapeutics Branch, NIMH, NIH, Bethesda, MD, USA

    D Pickar

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  1. D Pickar
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Pickar, D. The D2 receptor: love it and leave it. Mol Psychiatry 3, 101–102 (1998). https://doi.org/10.1038/sj.mp.4000364

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