Abstract
Wolfram syndrome is an autosomal recessive disorder caused by a gene on the short arm of chromosome 4 and characterized by a range of neurological, psychiatric and behavioural abnormalities. Recent research suggests that heterozygous carriers of the disease gene are at increased risk of psychiatric hospitalization.
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Owen, M. Psychiatric disorders in Wolfram syndrome heterozygotes. Mol Psychiatry 3, 12–13 (1998). https://doi.org/10.1038/sj.mp.4000349
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DOI: https://doi.org/10.1038/sj.mp.4000349