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ICE and apoptosis

Molecular Psychiatry volume 2, pages 184–187 (1997)Cite this article

Abstract

This issue features an article by Lynch, Shivers and colleagues (pages 227–238) which presents a novel, cell-permeable cysteine protease inhibitor, boc-aspartyl(OMe)-fluoromethylketone (boc-Asp-CH2F, abbreviated BAF). This inhibitor is an important new tool available to the research community and may represent a harbinger of a new class of chemicals useful in the treatment of human disease. In order to understand the value of BAF, we need to take a step back and examine the current concepts on the role of apoptosis in human disease.

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  1. Dept of Pharmacology, Loyola University Medical Center, Bldg 102, Rm 3634, 2160 South First Ave, Maywood, 60153, IL, USA

    B Wolozin

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  1. B Wolozin
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Wolozin, B. ICE and apoptosis. Mol Psychiatry 2, 184–187 (1997). https://doi.org/10.1038/sj.mp.4000243

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  • DOI: https://doi.org/10.1038/sj.mp.4000243

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