Abstract
Editor's Note: Can PDE5 inhibitors inhibit fibrosis? Is this a direct effect of PDE5 inhibitors on the fibrotic cascade? If this hypothesis is found true, then an entire new algorithm for treatment of ED and other diseases may be realized. Three recent manuscripts this year discuss this question. Dr Jackie Corbin, a renowned PDE5 expert, offers a perspective in light of its potential clinical relevance.
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Corbin, J. PDE5 inhibition and fibrosis. Int J Impot Res 17, 546 (2005). https://doi.org/10.1038/sj.ijir.3901362
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DOI: https://doi.org/10.1038/sj.ijir.3901362