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Heparin-induced priapism


Heparin-induced priapism constitutes a special form of pharmaco-induced prolonged erection, but the pathophysiological principles are not yet definitely clear. Heparin-induced antiplatelet-antibodies may lead to the aggregation of thrombocytes and thus alter the penile blood flow leading to low-flow priapism. Alternatively, this condition may be explained by initial high-flow priapism that later turns into ischemic priapism. The question remains whether hemorrhage with subsequent organisation of the hematoma and late fibrosis constitutes a pathogenetic factor. Besides this pathogenetic discussion, this paper presents the differential diagnosis of priapism as well as diagnostic and therapeutic procedures.

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  1. Melman A, Serels S. . Priapism. Int J Impot Res 2000 12(Suppl 4), S133–S139.

    Article  Google Scholar 

  2. DeHoll JD, Shin PA, Angle JF, Steers WD. . Alternative approaches to the management of priapism. Int J Impot Res 1998 10, 11–14.

    Article  CAS  Google Scholar 

  3. Duggan ML, Morgan C Jr. . Heparin: a cause of priapism? South Med J 1970 63, 1131–1134.

    Article  CAS  Google Scholar 

  4. Clark SK, Tremann JA, Sennewald FR, Donaldson JA. . Priapism: an unusual complication of heparin therapy for sudden deafness. Am J Otolaryngol 1981 2, 69–72.

    Article  CAS  Google Scholar 

  5. Adjiman S, Fava P, Bitker MO, Chatelain C. . Priapisme induit par I'héparine—un prognostic plus sombre? Ann Urol 1988 22, 125–128.

    CAS  Google Scholar 

  6. De Siati M et al.. Priapism as a complication of heparin therapy. Arch Ital Urol Androl 1999 71, 201–202.

    CAS  PubMed  Google Scholar 

  7. Klein LA, Hall RL, Smith RB. . Surgical treatment of priapsm: with a note on heparin-induced priapism. J Urol 1972 108, 104–106.

    Article  CAS  Google Scholar 

  8. Broderick GA, Harkaway R. . Pharmacologic erection: time-dependent changes in the corporal environment. Int J Impot Res 1994 6, 9–16.

    CAS  PubMed  Google Scholar 

  9. Juenemann KP et al.. Blood gas analysis in drug-induced penile erection. Urol Int 1986 41, 207–211.

    Article  CAS  Google Scholar 

  10. Winter CC. . Cure of idiopathic priapism: new procedure for creating fistula between glans penis and corpora cavernosa. Urology 1976 8, 389–391.

    Article  CAS  Google Scholar 

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Correspondence to EW Hauck.

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Bschleipfer, T., Hauck, E., Diemer, T. et al. Heparin-induced priapism. Int J Impot Res 13, 357–359 (2001).

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  • pathophysiology
  • fibrosis of the corpora cavernosa
  • priapism
  • heparin

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