This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Jaffe ES, Harris NL, Stein H, Vardiman JW (eds) World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. World Health Organization: Lyon, 2001, 135–137.
Dierlamm J, Rosenberg C, Stul M, Pittaluga S, Wlodarska I, Michaux L et al. Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization. Leukemia 1997; 11: 747–758.
Hernandez JM, Garcia JL, Gutierrez NC, Mollejo M, Martinez-Climent JA, Flores T et al. Novel genomic imbalances in B-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics. Am J Pathol 2001; 158: 1843–1850.
Boonstra R, Bosga-Bouwer A, van Imhoff GW, Krause V, Palmer M, Coupland RW et al. Splenic marginal zone lymphomas presenting with splenomegaly and typical immunophenotype are characterized by allelic loss in 7q31–32. Mod Pathol 2003; 16: 1210–1217.
Andersen CL, Gruszka-Westwood A, Ostergaard M, Koch J, Jacobsen E, Kjeldsen E et al. A narrow deletion of 7q is common to HCL, and SMZL, but not CLL. Eur J Haematol 2004; 72: 390–402.
Andersen CL, Gruszka-Westwood A, Atkinson S, Matutes E, Catovsky D, Pedersen RK et al. Recurrent genomic imbalances in B-cell splenic marginal-zone lymphoma revealed by comparative genomic hybridization. Cancer Genet Cytogenet 2005; 156: 122–128.
Gruszka-Westwood AM, Hamoudi R, Osborne L, Matutes E, Catovsky D . Deletion mapping on the long arm of chromosome 7 in splenic lymphoma with villous lymphocytes. Genes Chromosomes Cancer 2003; 36: 57–69.
Remstein ED, Dogan A, Einerson RR, Paternoster SF, Fink SR, Law M et al. The incidence and anatomic site specificity of chromosomal translocations in primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in North America. Am J Surg Pathol 2006; 30: 1546–1553.
Einerson RR, Law ME, Blair HE, Kurtin PJ, McClure RF, Ketterling RP et al. Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in B-cell lineage malignancy identify a new breakpoint cluster region designated BVR2. Leukemia 2006; 20: 1790–1799.
Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med 2007; 131: 18.
Qian J, Bostwick DG, Takahashi S, Borell TJ, Herath JF, Lieber MM et al. Chromosomal anomalies in prostatic intraepithelial neoplasia and carcinoma detected by fluorescence in situ hybridization. Cancer Res 1995; 55: 5408–5414.
Morrison AM, Jager U, Chott A, Schebesta M, Haas OA, Busslinger M . Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma. Blood 1998; 92: 3865–3878.
Andrieux J, Fert-Ferrer S, Copin MC, Huyghe P, Pocachard P, Lespinasse J et al. Three new cases of non-Hodgkin lymphoma with t(9;14)(p13;q32). Cancer Genet Cytogenet 2003; 145: 65–69.
Gazzo S, Baseggio L, Coignet L, Poncet C, Morel D, Coiffier B et al. Cytogenetic and molecular delineation of a region of chromosome 3q commonly gained in marginal zone B-cell lymphoma. Haematologica 2003; 88: 31–38.
Daibata M, Taguchi T, Nemoto Y, Iwasaki S, Ohtsuki Y, Taguchi H . In vitro Epstein–Barr virus-immortalized lymphoma cell line carrying t(9;14)(p13;q32) chromosome abnormality, derived from splenic lymphoma with villous lymphocytes. Int J Cancer 2006; 118: 513–517.
Dierlamm J, Pittaluga S, Stul M, Wlodarska I, Michaux L, Thomas J et al. BCL6 gene rearrangements also occur in marginal zone B-cell lymphoma. Br J Haematol 1997; 98: 719–725.
Aamot HV, Micci F, Holte H, Delabie J, Heim S . G-banding and molecular cytogenetic analyses of marginal zone lymphoma. Br J Haematol 2005; 130: 890–901.
Soma LA, Gollin SM, Remstein ED, Ketterling RP, Flynn HC, Rajasenan KK et al. Splenic small B-cell lymphoma with IGH/BCL3 translocation. Hum Pathol 2006; 37: 218–230.
Oscier DG, Gardiner A, Mould S . Structural abnormalities of chromosome 7q in chronic lymphoproliferative disorders. Cancer Genet Cytogenet 1996; 92: 24–27.
Brito-Babapulle V, Gruszka-Westwood AM, Platt G, Andersen CL, Elnenaei MO, Matutes E et al. Translocation t(2;7)(p12;q21–22) with dysregulation of the CDK6 gene mapping to 7q21–22 in a non-Hodgkin's lymphoma with leukemia. Haematologica 2002; 87: 357–362.
Corcoran MM, Mould SJ, Orchard JA, Ibbotson RE, Chapman RM, Boright AP et al. Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations. Oncogene 1999; 18: 6271–6277.
Sonoki T, Harder L, Horsman DE, Karran L, Taniguchi I, Willis TG et al. Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies. Blood 2001; 98: 2837–2844.
Dierlamm J, Pittaluga S, Wlodarska I, Stul M, Thomas J, Boogaerts M et al. Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features. Blood 1996; 87: 1299–1307.
Camacho FI, Mollejo M, Mateo MS, Algara P, Navas C, Hernandez JM et al. Progression to large B-cell lymphoma in splenic marginal zone lymphoma: a description of a series of 12 cases. Am J Surg Pathol 2001; 25: 1268–1276.
Sole F, Salido M, Espinet B, Garcia JL, Martinez Climent JA, Granada I et al. Splenic marginal zone B-cell lymphomas: two cytogenetic subtypes, one with gain of 3q and the other with loss of 7q. Haematologica 2001; 86: 71–77.
Martinez-Climent JA, Sanchez-Izquierdo D, Sarsotti E, Blesa D, Benet I, Climent J et al. Genomic abnormalities acquired in the blastic transformation of splenic marginal zone B-cell lymphoma. Leuk Lymphoma 2003; 44: 459–464.
Oscier DG . Cytogenetic and molecular abnormalities in chronic lymphocytic leukaemia. Blood Rev 1994; 8: 88–97.
Jadayel D, Matutes E, Dyer MJ, Brito-Babapulle V, Khohkar MT, Oscier D et al. Splenic lymphoma with villous lymphocytes: analysis of BCL-1 rearrangements and expression of the cyclin D1 gene. Blood 1994; 83: 3664–3671.
Cuneo A, Bardi A, Wlodarska I, Selleslag D, Roberti MG, Bigoni R et al. A novel recurrent translocation t(11;14)(p11;q32) in splenic marginal zone B cell lymphoma. Leukemia 2001; 15: 1262–1267.
Acknowledgements
This work was supported in part by Grant CA97274 from the National Institutes of Health, Bethesda, MD, USA.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Remstein, E., Law, M., Mollejo, M. et al. The prevalence of IG translocations and 7q32 deletions in splenic marginal zone lymphoma. Leukemia 22, 1268–1272 (2008). https://doi.org/10.1038/sj.leu.2405027
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2405027
This article is cited by
-
IRF4 Gene Rearrangements Define a Subgroup of CD30-Positive Cutaneous T-Cell Lymphoma: A Study of 54 Cases
Journal of Investigative Dermatology (2010)
-
PAX5-positive T-cell anaplastic large cell lymphomas associated with extra copies of the PAX5 gene locus
Modern Pathology (2010)
-
Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas
Leukemia (2009)