Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Reply to ‘Imatinib induces apoptosis in CLL lymphocytes with high expression of Par-4’ by Chow et al

Leukemia volume 19, pages 1105–1106 (2005)Cite this article

TO THE EDITOR

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1

References

  1. Chow KU, Nowak D, Hofmann W, Schneider B, Hofmann W-K . Imatinib induces apoptosis in CLL lymphocytes with high expression of Par-4. Leukemia 2005, April 7 [E-pub ahead of print].

  2. Aloyz R, Grzywacz K, Xu ZY, Loignon M, Alaoui-Jamali MA, Panasci L . Imatinib sensitizes CLL lymphocytes to chlorambucil. Leukemia 2004; 18: 409–414.

    Article  CAS  Google Scholar 

  3. King D, Pringle JH, Hutchinson M, Cohen GM . Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells. Leukemia 1998; 12: 1553–1560.

    Article  CAS  Google Scholar 

  4. Huang Y, Nakada S, Ishiko T, Utsugisawa T, Datta R, Kharbanda S et al. Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol Cell Biol 1999; 19: 2986–2997.

    Article  CAS  Google Scholar 

  5. Yuan ZM, Huang Y, Ishiko T, Nakada S, Utsugisawa T, Kharbanda S et al. Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem 1998; 273: 3799–3802.

    Article  CAS  Google Scholar 

  6. Slupianek A, Schmutte C, Tombline G, Nieborowska-Skorska M, Hoser G, Nowicki MO et al. BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance. Mol Cell 2001; 8: 795–806.

    Article  CAS  Google Scholar 

  7. Conilleau S, Takizawa Y, Tachiwana H, Fleury F, Kurumizaka H, Takahashi M . Location of tyrosine 315, a target for phosphorylation by cAbl tyrosine kinase, at the edge of the subunit-subunit interface of the human Rad51 filament. J Mol Biol 2004; 339: 797–804.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Lady Davis Institute for Medical Research, Sir Mortimer B Davis – Jewish General Hospital, Montréal, Quebec, Canada

    R Aloyz & L Panasci

Authors
  1. R Aloyz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L Panasci
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to L Panasci.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aloyz, R., Panasci, L. Reply to ‘Imatinib induces apoptosis in CLL lymphocytes with high expression of Par-4’ by Chow et al. Leukemia 19, 1105–1106 (2005). https://doi.org/10.1038/sj.leu.2403740

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2403740

This article is cited by

Search

Advanced search

Quick links