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Successful treatment of hyperuricemia with low doses of recombinant urate oxidase in four patients with hematologic malignancy and tumor lysis syndrome

Leukemia volume 17, pages 2542–2544 (2003)Cite this article

TO THE EDITOR

Tumor lysis syndrome commonly occurs in patients with acute leukemia and non-Hodgkin's lymphoma with a high tumor burden, even before any antineoplastic treatment is given. Severe complications like hyperkalemia and renal failure induced by uric acid and/or calcium phosphate crystals can arise.

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  1. III. Medizinische Klinik, Universitaetsklinikum Mannheim, University of Heidelberg, Mannheim, Germany

    M Hummel, D Buchheidt, S Reiter, J Bergmann, R Hofheinz & R Hehlmann

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  1. M Hummel
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  2. D Buchheidt
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  3. S Reiter
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Hummel, M., Buchheidt, D., Reiter, S. et al. Successful treatment of hyperuricemia with low doses of recombinant urate oxidase in four patients with hematologic malignancy and tumor lysis syndrome. Leukemia 17, 2542–2544 (2003). https://doi.org/10.1038/sj.leu.2403161

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