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  • Meeting Report and Mini Review
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Dendritic cells: interfaces with immunobiology and medicine. A report from the Keystone Symposia Meeting held in Keystone, 3–8 March 2003

Abstract

Dendritic cells (DCs) are the most potent antigen-presenting cells in vitro and in vivo. They play a key role in the initiation of the immune response and are considered promising targets for immunotherapy. The recent DC Keystone Symposia, organized by Ralph M Steinman, Anne O'Garra and Jacques Banchereau, was held on 3–8 March 2003 in Keystone (CO, USA). This multidisciplinary meeting developed various areas related to the DC biology including: (i) DC and the control of immunity vs tolerance; (ii) DC maturation and manipulation for immunotherapy in vivo; and (iii) antigen capture by DC in situ and interactions with microbial pathogens. The aim of this report is to present some of the highlights developed during the meeting and debated among the DC community.

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Acknowledgements

We would like to acknowledge the ‘Fondation de France (FDF)’, the ‘Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC)’, the ‘Fondation pour la Recherche Medicale (FRM)’, the ‘Association Sang pour Cent la Vie’ (Paris, France), the ‘Ligue Departementale du Gard contre le Cancer’ (Nimes, France), the ‘Association pour la Recherche sur le Cancer (ARC)’, the ‘Ligue Nationale contre le Cancer’ and the GEFLUC for their generous support for our ongoing clinical and basic research work. We also thank Daniel Olive (Laboratoire d'Immunologie des Tumeurs, Institut Paoli-Calmettes) and Didier Blaise (UTTC, Institut Paoli-Calmettes) for their continuous support and helpful discussions.

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Mohty, M., Gaugler, B. Dendritic cells: interfaces with immunobiology and medicine. A report from the Keystone Symposia Meeting held in Keystone, 3–8 March 2003. Leukemia 17, 1753–1758 (2003). https://doi.org/10.1038/sj.leu.2403049

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