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Complete remission of subcutaneous panniculitic T-cell lymphoma after allogeneic transplantation

Bone Marrow Transplantation volume 38, pages 821–822 (2006)Cite this article

A 15-year-old girl presented with a 2-month history of nodules on the arm. The initial biopsy showed an unspecific granulomatous reaction that was reported as non-diagnostic. Four months later, more nodules appeared in other locations and the pre-existing nodules had increased in size. Fever between 37.5 and 38°C also appeared. A new histological evaluation showed an acute inflammatory infiltration, consisting of lymphocytes and monocytes, compatible with septal and lobular panniculitis. A short course of steroids was started, resulting in partial resolution of nodules and disappearance of fever.

Blood count showed: haemoglobin 10.1 g/dl, white cell count 3.3 × 109/l and platelet count 202 × 109/l. C-reactive protein was 5.7 mg/dl, beta 2 microglobulin 4 mg/l and erythrocyte sedimentation rate was 72 mm/h, lactate dehydrogenase (LDH) 936 mg/dl, transaminases: glutamic oxaloacetic transaminase 48 mg/dl and glutamic pyruvic transaminase 27 mg/dl. Serology for hepatitis A, B and C, herpes, cytomegalovirus and Epstein–Barr virus (EBV) as well as Brucella, were all negative. Rheumatological tests were also negative.

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  1. Deparment of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain

    E Pérez-Persona, J J Mateos-Mazón, O López-Villar, M J Arcos, C Encinas, I F Graciani, E M Ocio, F M Sánchez-Guijo & M D Caballero

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  1. E Pérez-Persona
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Correspondence to M D Caballero.

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Pérez-Persona, E., Mateos-Mazón, J., López-Villar, O. et al. Complete remission of subcutaneous panniculitic T-cell lymphoma after allogeneic transplantation. Bone Marrow Transplant 38, 821–822 (2006). https://doi.org/10.1038/sj.bmt.1705527

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