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CO2 laser in oral graft-versus-host disease: a pilot study

Bone Marrow Transplantation volume 32, pages 1031–1034 (2003)Cite this article

Summary:

This paper is the first to report the benefits of CO2 laser treatment for pain control in severe oral chronic graft-versus-host disease (GVHD). A CO2 laser device was used during 17 treatment sessions in four patients. The CO2 laser was applied over the mucosal lesions using 1 W for 2–3 s/1 mm2. This treatment resulted in a consistent and significant decrease in pain, measured using a standard visual analogue scale. These results suggest that the CO2 laser can be used for the alleviation of pain in oral chronic GVHD.

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Acknowledgements

We would like to thank Dr Sharon DM Robinson for the editorial assistance. We would like to thank ESCq/Sharplan/Luxar group – Lumenis™ (OpusDent™) for facillitating the treatment with the Opus20™ device.

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Authors and Affiliations

  1. Oral Medicine Department, The Hebrew University-Hadassah School of Dental Medicine founded by the Alpha Omega Fraternity, Jerusalem, Israel

    S Elad, A Haviv, D Galili, A A Garfunkel & E Kaufman

  2. Bone Marrow Transplantation Department, Hadassah University Hospital, Jerusalem, Israel

    R Or, M Y Shapira & M Bitan

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  1. S Elad
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  2. R Or
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  3. M Y Shapira
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  4. A Haviv
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  5. D Galili
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  6. A A Garfunkel
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  7. M Bitan
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  8. E Kaufman
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Correspondence to S Elad.

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Elad, S., Or, R., Shapira, M. et al. CO2 laser in oral graft-versus-host disease: a pilot study. Bone Marrow Transplant 32, 1031–1034 (2003). https://doi.org/10.1038/sj.bmt.1704272

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