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Invasive airway aspergillosis with new airflow obstruction mimicking post-BMT bronchiolitis obliterans

Bone Marrow Transplantation volume 29, pages 711–713 (2002)Cite this article

Abstract

A 52-year-old male with severe gastrointestinal graft-versus-host disease (GVHD), developed dyspnea and irreversible airflow obstruction, 11 weeks post-allogeneic bone marrow stem cell transplantation. Based on the clinical picture and presence of ‘mosaic attenuation’ pattern on chest high-resolution computerized tomography (HRCT), he was presumed to have bone marrow transplantation-related bronchiolitis obliterans. Postmortem examination revealed invasive airway aspergillosis with no evidence of bronchiolitis obliterans.

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References

  1. Soubani AO, Miller KB, Hassoun PM . Pulmonary complications of bone marrow transplantation Chest 1996 109: 1066 1077

    Article  CAS  Google Scholar 

  2. Blum U, Windfuhr M, Buitrago-Tellez C et al. Invasive pulmonary aspergillosis: MRI, CT, and plain radiographic findings and their contribution for early diagnosis Chest 1994 106: 1156 1161

    Article  CAS  Google Scholar 

  3. Clarke A, Skelton J, Fraser RS . Fungal tracheobronchitis: report of nine cases and review of the literature Medicine 1991 70: 1 14

    Article  CAS  Google Scholar 

  4. Hines DW, Haber MH, Yaremko L et al. Pseudomembranous tracheobronchitis caused by aspergillus Am Rev Respir Dis 1991 143: 1408 1411

    Article  CAS  Google Scholar 

  5. Kramer MR, Denning DW, Marshall SE et al. Ulcerative tracheobronchitis after lung transplantation: a new form of invasive aspergillosis Am Rev Respir Dis 1991 144: 552 556

    Article  CAS  Google Scholar 

  6. Logan PM, Primack SL, Miller RR et al. Invasive aspergillosis of the airways: radiographic, CT, and pathologic findings Radiology 1994 193: 383 388

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Pulmonology, Hadassah University Hospital and Hebrew University-Hadassah School of Medicine, Jerusalem, Israel

    S Nusair & R Breuer

  2. Department of Pathology, Hadassah University Hospital and Hebrew University-Hadassah School of Medicine, Jerusalem, Israel

    G Amir

  3. Department of Bone Marrow Transplantation, Hadassah University Hospital and Hebrew University-Hadassah School of Medicine, Jerusalem, Israel

    R Or

Authors
  1. S Nusair
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  2. G Amir
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  3. R Or
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  4. R Breuer
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Nusair, S., Amir, G., Or, R. et al. Invasive airway aspergillosis with new airflow obstruction mimicking post-BMT bronchiolitis obliterans. Bone Marrow Transplant 29, 711–713 (2002). https://doi.org/10.1038/sj.bmt.1703553

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  • DOI: https://doi.org/10.1038/sj.bmt.1703553

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