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Four patients with AL amyloidosis treated with high-dose chemotherapy and autologous stem cell transplantation

Abstract

Four patients with AL amyloidosis underwent high-dose chemotherapy and autologous stem cell transplantation at our institutions. Here, we report the clinical courses and outcomes in these patients. Two patients with multi-organ amyloid deposits including cardiac involvement died within 12 days after high-dose chemotherapy. However, in the other two patients, one of whom was suffering from amyloid-related cardiac failure, a significant improvement of organ function was achieved. Bone Marrow Transplantation (2001) 27, 341–343.

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Reich, G., Held, T., Siegert, W. et al. Four patients with AL amyloidosis treated with high-dose chemotherapy and autologous stem cell transplantation. Bone Marrow Transplant 27, 341–343 (2001). https://doi.org/10.1038/sj.bmt.1702766

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