Abstract
Post-transplant lymphoproliferative disorders (PTLD) of T cell type are a rare complication of solid organ and allogeneic hematopoietic cell transplantation (HCT), and usually are not associated with Epstein–Barr virus (EBV) infection. EBV-associated T cell PTLD has not been reported to occur after autologous HCT. We report an unusual case of T cell lymphoproliferation after autologous blood stem cell transplantation (ABSCT). A patient with relapsed Hodgkin's disease developed abdominal lymphadenopathy followed by atypical CD8+lymphocytosis in the peripheral blood 30 months following ABSCT. DNA studies of the atypical lymphocytes demonstrated rearrangements of the T cell receptor β gene and a clonal proliferation of EBV. Bone Marrow Transplantation (2000) 26, 1339–1341.
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Yufu, Y., Kimura, M., Kawano, R. et al. Epstein–Barr virus-associated T cell lymphoproliferative disorder following autologous blood stem cell transplantation for relapsed Hodgkin's disease. Bone Marrow Transplant 26, 1339–1341 (2000). https://doi.org/10.1038/sj.bmt.1702721
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DOI: https://doi.org/10.1038/sj.bmt.1702721
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