Abstract
Although recipients of unrelated cord blood can tolerate a greater degree of HLA-disparity than recipients of unrelated bone marrow, cell dose is also important. After an unsuccessful search for a bone marrow donor, and after initially dismissing a cord blood search because the patient was 52 kg, we used a different search strategy to identify an unrelated cord blood unit. This led to successful engraftment and transplantation for a patient with no bone marrow donor. Bone Marrow Transplantation (2000) 26, 585–586.
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References
Locatelli F, Rocha V, Chastang C et al. Factors associated with outcome after cord blood transplantation in children with acute leukaemia Blood 1999 93: 3662–3671
Rubenstein P, Carrier C, Scaradavou A et al. Outcomes among 562 recipients of placental-blood transplants from unrelated donors New Engl J Med 1998 339: 1565–1577
Acknowledgements
Vicki Antonenas provided expert care in the thawing and reinfusion of this precious unit. Marie Bleakley is supported by the Leukaemia Research and Support Fund.
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Bleakley, M., Shaw, P. Searching for a cord blood unit for transplantation based on the unit's cell count. Bone Marrow Transplant 26, 585–586 (2000). https://doi.org/10.1038/sj.bmt.1702560
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DOI: https://doi.org/10.1038/sj.bmt.1702560